KRAS 8 Suiga

Fa'amatalaga Puupuu:

O lenei pusa ua fa'amoemoe mo le su'esu'eina fa'apitoa i vitro o suiga e 8 i codons 12 ma le 13 o le K-ras gene i le DNA na maua mai i vaega fa'ama'i fa'apipi'i a tagata.


Fa'amatalaga Oloa

Faailoga o oloa

Igoa o oloa

HWTS-TM014-KRAS 8 Su'esu'ega Pusa (Fluorescence PCR)

HWTS-TM011-Aisa-mamago KRAS 8 Su'esu'ega Pusa (Fluorescence PCR)

Tusi Faamaonia

CE

Epidemiology

O suiga mata'ina i le KRAS gene ua maua i le tele o ituaiga tumo tagata, e uiga i le 17% ~ 25% fua faatatau mutation i le tuma, 15% ~ 30% fua faatatau mutation i gasegase kanesa mama, 20% ~ 50% fua faatatau mutation i le kanesa colorectal gasegase.Talu ai ona o le polotini P21 o loʻo faʻapipiʻiina e le K-ras gene o loʻo i lalo ifo o le ala faʻailoga EGFR, pe a maeʻa le suiga o le K-ras gene, o le ala faʻailoga pito i lalo e masani ona faʻagaoioia ma e le aʻafia i fualaau faʻatatau i luga ole EGFR, e mafua ai le faʻaauau pea. fa'atupu leaga o sela.O suiga i le kenera K-ras e masani ona maua ai le tetee atu i le EGFR tyrosine kinase inhibitors i tagata mama'i kanesa ma le tetee atu i le anti-EGFR antibody drugs i tagata mama'i kanesa colorectal.I le 2008, na tuʻuina atu ai e le National Comprehensive Cancer Network (NCCN) se taʻiala faʻataʻitaʻi mo le kanesa colorectal, lea na faʻaalia ai o nofoaga o suiga e mafua ai ona faʻagaoioia K-ras e tele lava ina maua i codons 12 ma le 13 o le exon 2, ma fautuaina e faapea. o tagata mama'i uma e maua i le kanesa colorectal metastatic maualuga e mafai ona tofotofoina mo K-ras mutation a'o le'i togafitia.O le mea lea, o le vave ma le saʻo o le suʻesuʻeina o K-ras gene mutation e taua tele i le taʻitaʻiga o vailaʻau.O lenei pusa o loʻo faʻaogaina le DNA e fai ma faʻataʻitaʻiga faʻataʻitaʻiga e tuʻuina atu ai suʻesuʻega agavaʻa o le tulaga o suiga, lea e mafai ona fesoasoani i fomaʻi ile suʻesuʻeina o le kanesa colorectal, kanesa o le mama ma isi tagata mamaʻi o loʻo manuia mai vailaʻau faʻatatau.O fa'ai'uga o su'ega a le pusa e mo na'o fa'amatalaga fa'afoma'i ma e le tatau ona fa'aaogaina e na'o le fa'avae mo togafitiga ta'ito'atasi o gasegase.E tatau i foma'i ona faia ni fa'ai'uga atoatoa i fa'ai'uga o su'ega e fa'atatau i mea e pei o le tulaga o le ma'i, fa'ailoga o vaila'au, tali o togafitiga ma isi fa'ailoga o su'ega su'esu'e.

Vaega Fa'ainisinia

Teuina Suavai: ≤-18 ℃ I le pogisa;Lyophilized: ≤30 ℃ I le pogisa
Fa'asa-ola Suavai: 9 masina;Lyophilized: 12 masina
Ituaiga Fa'ata'ita'iga o aano po'o se vaega o lo'o iai paraffini o lo'o iai sela tumo
CV ≤5.0%
LoD O le K-ras Reaction Buffer A ma le K-ras Reaction Buffer B e mafai ona mautu le 1% fua faatatau o suiga i lalo ole 3ng/μL vao-ituaiga talaaga.
Meafaigaluega Faatatau Fa'aogaina Biosystems 7500 Fa'atonu PCR Taimi Moni

Fa'aogaina Biosystems 7300 Fa'atonu PCR Taimi Moni

QuantStudio®5 Faiga PCR Taimi Moni

LightCycler® 480 Taimi moni PCR faiga

BioRad CFX96 Taimi Moni PCR System

Galulue Galuega

E fautuaina e fa'aoga le QIAGEN's QIAamp DNA FFPE Tissue Kit (56404) ma Paraffin-embedded Tissue DNA Rapid Extraction Kit (DP330) gaosia e Tiangen Biotech(Beijing) Co., Ltd.


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