Human Leukocyte Antigen B27 Nucleic Acid
Igoa o oloa
HWTS-GE011A-Human Leukocyte Antigen B27 Nucleic Acid Detection Kit (Fluorescence PCR)
Epidemiology
O le Ankylosing spondylitis (AS) o se faʻamaʻi faʻasolosolo faʻasolosolo e masani ona osofaʻia le tui ma e ono aʻafia ai sooga sacroiliac ma sooga siʻosiʻomaga i tulaga eseese.Ua fa'ailoa mai o le AS o lo'o fa'aalia le fa'aputuga fa'apitoa o aiga ma e feso'ota'i vavalalata ma le tagata leukocyte antigen HLA-B27.I totonu o tagata, e sili atu i le 70 ituaiga o HLA-B27 subtypes ua maua ma iloa, ma oi latou, HLA-B*2702, HLA-B*2704 ma HLA-B*2705 o la'ititi masani ia e feso'ota'i ma le ma'i.I Saina, Sigapoa, Iapani ma Taiuani itumalo o Saina, o le subtype masani o le HLA-B27 o le HLA-B*2704, e tusa ma le 54%, sosoo ai ma le HLA-B*2705, lea e tusa ma le 41%.O lenei pusa e mafai ona iloa le DNA i subtypes HLA-B*2702, HLA-B*2704 ma HLA-B*2705, ae e le fa'aesea mai le tasi i le isi.
Auala
| FAM | HLA-B27 |
| VIC/HEX | Pulea i totonu |
Vaega Fa'ainisinia
| Teuina | Suavai: ≤-18℃ I le pogisa |
| Fa'asa-ola | Suavai: 18 masina |
| Ituaiga Fa'ata'ita'iga | fa'ata'ita'iga toto atoa |
| Ct | ≤40 |
| CV | ≤5.0% |
| LoD | 1ng/μL |
| Fa'apitoa
| O fa'ai'uga o su'ega e maua mai i lenei pusa o le a le a'afia i le hemoglobin (<800g/L), bilirubin (<700μmol/L), ma le toto lipids/triglycerides (<7mmol/L) ile toto. |
| Meafaigaluega Faatatau | Fa'aogaina Biosystems 7500 Fa'atonu PCR Taimi Moni Applied Biosystems StepOne Real-Time PCR Systems LightCycler®480 Taimi moni PCR faiga Agilent-Stratagene Mx3000P Q-PCR System |
